Creating Health Equity Through Global Genomics Research

Members

Meet our distinguished members
Joan O'Brien

Joan O'Brien, MD

Chair, Dept of Ophthalmology
Director, Scheie Eye Institute

The lead investigator on the Primary Open-Angle African American Glaucoma Genetics (POAAGG) studying the genetics of ocular diseases. Especially interested in the genetics of retinoblastoma, uveal melanoma, and glaucoma.
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Susan Taylor

Susan C. Taylor, MD

Associate Professor of Dermatology,
Univ of Pennsylvania

A clinician-educator who has pioneered and profoundly influenced the field of dermatology by establishing and defining Skin of Color dermatology as an area of sub-specialty. She works to advance and promote clinical knowledge of the unique needs and treatment challenges posed by ethnic skin and hair.
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Li-San_Wang

Li-San Wang, PhD

Professor of Pathology & Laboratory Medicine; Co-Director, Penn Neurodegeneration Genomics Center

My interest is in studying the genetics of Alzheimer's disease and related dementia in diverse populations with focus on Asian populations in Asia and North America. Founded the Asian Cohort for Alzheimer's Disease (ACAD).
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Anne_Marie_McCarthy

Anne Marie McCarthy, ScM, PhD

Assistant Professor
Dept. of Biostatistics, Epidemiology, and Informatics (DBEI), Univ. of Pennsylvania

A cancer epidemiologist, whose research aims to reduce the burden of cancer, particularly among ethnic minorities, through innovative approaches to cancer prevention and early detection. My work seeks to integrate genetic, molecular, and imaging biomarkers to better predict and detect poor prognosis breast cancers.
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Iain

Iain Mathieson, PhD

Associate Professor of Genetics

My lab uses statistical and population genetic methods to investigate the evolution and genetic basis of complex traits in humans. We develop statistical methods to predict complex traits including disease risk across diverse populations, and use both ancient and modern DNA to study the evolution of those traits.
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Rachel-Werner

Rachel M. Werner, MD, PhD

Executive Director, Leonard Davis Institute of Health Economics
Robert D. Eilers Professor, Health Care Management - Wharton School

Seeks to understand the effect of health care policies and delivery systems on quality of care. In particular, she has examined the role of quality improvement incentives on provider behavior, the organization of health care, racial disparities, and overall health care quality.
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Steven-Joffe

Steven Joffe, MD, MPH

Chief, Division of Medical Ethics
Founders Professor of Medical Ethics and Health Policy

My research focuses on ethical, regulatory, and policy challenges in medicine and science, with a particular emphasis on the ethical, legal, and social implications (ELSI) of genomics.
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Rachel-Werner

Gerd Blobel, MD, PhD

Frank E. Weise III Professor of Pediatrics
Co-Director UPENN Epigenetics Institute

The Blobel lab focuses on the genetic and epigenetic control of hematopoiesis and its disorders. One special emphasis of the lab is to understand the control of the β-globin gene cluster. Efforts are underway to improve treatment of diseases that affect the globin genes such as sickle cell disease and β-thalassemia.
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Elizabeth-Bhoj

Elizabeth Bhoj, MD, PhD

Assistant Professor of Pediatrics & Genetics

Discovers new human disease genes, their mechanisms, and potential targeted therapies. In addition to ongoing gene discovery efforts, the lab focuses on three novel genes that lead to pediatric neurologic dysfunction: TBCK, H3F3A/B, and MAP4K4. A bedside-to-bench-to-bedside translational lab, bringing discoveries back to the patients. An area of intense focus is bringing clinical and molecular genetics research to areas without current local infrastructure.
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Rachel-Kember

Rachel L. Kember, PhD, M.Sc.

Assistant Professor of Psychiatry

My research focuses on the phenotypic architecture of common genetic risk for substance use and psychiatric disorders using data from large-scale biobanks with linked electronic health records (EHR). I am co-chair of the PsycheMERGE Diversity Initiative, a multi-site effort to address disparities in psychiatric genetics research by combining multi-ancestral data across EHR sites.
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Danielle-Reed

Danielle Reed, PhD

Associate Director, Monelle Chemical Senses Center

Bitter taste in medicines constitutes a global public health challenge because of poor compliance with medication use. In humans, not everyone perceives bitterness in the same way in part due to inborn genetic differences in the bitter taste receptor gene family. We are developing reliable, human taste-cell screening platforms from ethnically diverse people to find bitter blockers with the ultimate aim to improve the taste and acceptance of perniciously bitter medicines for all people globally.
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Carmen-Guerra

Carmen E. Guerra, MD, M.S.C.E., F.A.C.P.

Associate Director of Diversity and Outreach, Abramson Cancer Center
Advisory Dean, Dr. Helen O. Dickens House

A cancer control researcher whose research seeks to better understand and design interventions to overcome barriers to accessing cancer screening and cancer clinical trials. Dr. Guerra established a colorectal cancer screening navigation program and a breast cancer screening navigation program for underserved individuals in Philadelphia which have screened over 3000 individuals for cancer.
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